IFITM2 antibody (AA 1-132)

Catalog No. ABIN7673394

The Mouse Monoclonal anti-IFITM2 antibody has been validated for WB, ELISA and FACS. It is suitable to detect IFITM2 in samples from Human.

Quick Overview for IFITM2 antibody (AA 1-132) (ABIN7673394)

Target: IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IFITM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 9C2

Product Details anti-IFITM2 Antibody

Binding Specificity: AA 1-132

Purpose: IFITM2-specific antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-132aa

Immunogen: interferon induced transmembrane protein 2

Isotype: IgG1

Application Details

Application Notes: WB: 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for IFITM2

Target: IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))

Alternative Name: IFITM2

Background:

Synonyms: Interferon-induced transmembrane protein 2|Dispanin subfamily A member 2c (DSPA2c)|Interferon-inducible protein 1-8D|IFITM2

Background: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus(SARS-CoV), Marburg virus(MARV), Ebola virus(EBOV), Dengue virus(DNV), West Nile virus(WNV), human immunodeficiency virus type 1(HIV-1) and vesicular stomatitis virus(VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.

Molecular Weight: 15 kDa

Gene ID: 10581

UniProt: Q01629