CD20 antibody (PE-Cy5)

Catalog No. ABIN7673874

The Rat Monoclonal anti-CD20 antibody has been validated for FACS. It is suitable to detect CD20 in samples from Mouse.

Quick Overview for CD20 antibody (PE-Cy5) (ABIN7673874)

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD20 antibody is conjugated to PE-Cy5

Application: Flow Cytometry (FACS)

Clone: SA271G2

Product Details anti-CD20 Antibody (PE-Cy5)

Purpose: PE-Cy5 Anti-Mouse CD20 Antibody

Purification: 0

Purity: 0

Isotype: IgG2b, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for CD20

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Alternative Name: CD20

Background:

Synonyms: 0

Background: CD20 is a 33-37 kD protein, a member of the MS4A family, with four transmembrane spanning regions that present as a homo-oligomeric complexes in the cell surface when associating with MHC class I and II, CD53, CD81, and CD82. CD20 is expressed on B cells and a subset of T cells, but not on plasma cells. CD20 regulates B-cell activation and proliferation. Its ligation promotes transmembrane Ca2+ trafficking. CD20 is an important therapeutic target in the treatment of B cell lymphomas and leukemias.

Molecular Weight: 0

Gene ID: 12482

UniProt: P19437