CD44 antibody (PE-Cy7)

Catalog No. ABIN7674056

This Mouse Monoclonal antibody specifically detects CD44 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD44 antibody (PE-Cy7) (ABIN7674056)

Target: CD44

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD44 antibody is conjugated to PE-Cy7

Application: Flow Cytometry (FACS)

Clone: P2A1

Product Details anti-CD44 Antibody (PE-Cy7)

Purpose: PE-Cy7 Anti-Human CD44 Antibody

Purification: 0

Purity: 0

Isotype: IgG2a, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for CD44

Target: CD44

Alternative Name: CD44

Background:

Synonyms: MDU2MDU3MIC4|CD44|CD44 antigen|CDw44|Epican|LHR|PGP-1|PGP-I|Phagocytic glycoprotein 1|Phagocytic glycoprotein I

Background: CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

Molecular Weight: 0

Gene ID: 960

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling