CD16 antibody

Catalog No. ABIN7674445

This anti-CD16 antibody is a Rat Monoclonal antibody detecting CD16 in FACS and BR. Suitable for Mouse.

Quick Overview for CD16 antibody (ABIN7674445)

Target: CD16

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD16 antibody is un-conjugated

Application: Flow Cytometry (FACS), Blocking Reagent (BR)

Clone: 2-4G2

Product Details anti-CD16 Antibody

Purpose: Purified Anti-Mouse CD16/32 Antibody

Purification: Protein A+G purification

Purity: ≥98 % as determined by SDS-PAGE

Immunogen: Recombinant Mouse CD16/32 protein

Isotype: IgG2b, kappa

Application Details

Application Notes: The suggested use of this reagent is ≤ 1.0 μg per million cells in 100 μL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 2-8°C valid for 12 months or -20°C valid for long term storage, avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CD16

Target: CD16

Alternative Name: CD16

Background:

Synonyms: CD16a/b|CD32|CD32A/B|FCG2A|FCGR2A/BFCGR3|FCGR3A/B|Fc fragment of IgG low affinity IIIa/b receptor|Fc fragment of IgG low affinity IIIb receptor|Fc fragment of IgG low affinity IIa/b receptor|Fc gamma RIIa/b |Fc gamma receptor III A/B|FcGR|CD16/32

Background: CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

Gene ID: 14130

UniProt: P08508, P08101

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process