TTF1 antibody

Catalog No. ABIN7674575

This Mouse Monoclonal antibody specifically detects TTF1 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for TTF1 antibody (ABIN7674575)

Target: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TTF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 7C4

Product Details anti-TTF1 Antibody

Purpose: TTF1-Specific antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: transcription termination factor, RNA polymerase I

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for TTF1

Target: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Alternative Name: TTF1

Background:

Synonyms: Transcription termination factor 1 (TTF-1)|RNA polymerase I termination factor|Transcription termination factor I (TTF-I)|TTF1

Background: TTF1 is a multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. It plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5, TTF1 recovers DNA-binding activity. The antibody is specific to TTF1.

Molecular Weight: 43 kDa, 66 kDa

Gene ID: 7270

UniProt: Q15361

Pathways: Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour