WARS1 (AA 170-250) antibody

Catalog No. ABIN7674598

The Rabbit Polyclonal anti-WARS1 antibody (ABIN7674598) specifically detects WARS1 in ELISA, IHC and WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for WARS1 (AA 170-250) antibody (ABIN7674598)

Target: WARS1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Product Details

Binding Specificity: AA 170-250

Purpose: WARS1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 170-250aa

Immunogen: tryptophanyl-tRNA synthetase

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details

Target: WARS1

Background:

Synonyms: Tryptophan--tRNA ligase, cytoplasmic|Interferon-induced protein 53 (IFP53)|Tryptophanyl-tRNA synthetase (TrpRS, hWRS)|T1-TrpRS|T2-TrpRS|WARS1|IFI53|WARS|WRS

Background: TrpRS is also named as IFI53, WRS, WARS and belongs to the class-I aminoacyl-tRNA synthetase family. It catalyzes activation of tryptophan by ATP and transfer to tRNATrP, ensuring ranslation of the genetic code for tryptophan. TrpRS is thought to be more closely related to TyrRS than to any other class I enzyme, but the significance of this relationship has been questioned(PMID:7743129). It can exsit as a dimer(PMID:7743129). It has 2 isoforms produced by alternative splicing.

Molecular Weight: 53 kDa, 48 kDa

Gene ID: 7453

UniProt: P23381