L-Selectin antibody (FineTest®Violet 450)

Catalog No. ABIN7675146

This Mouse Monoclonal antibody specifically detects L-Selectin in FACS. It exhibits reactivity toward Human.

Quick Overview for L-Selectin antibody (FineTest®Violet 450) (ABIN7675146)

Target: L-Selectin (SELL) (Selectin L (SELL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This L-Selectin antibody is conjugated to FineTest®Violet 450

Application: Flow Cytometry (FACS)

Clone: HI62L

Product Details anti-L-Selectin Antibody (FineTest®Violet 450)

Purpose: FineTest®Violet 450 Anti-Human CD62L Antibody

Isotype: IgG2a, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Comment:

FineTest®Violet Dyes are designed to be excited by the violet laser at 405 nm

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Alternative Name: CD62L

Background:

Synonyms: L-selectin|Sell|CD62 antigen-like family member L|LAM-1|LECAM1|Lymph node homing receptor|Ly-22|CD62L|Lnhr|Ly22

Background: CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naive lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

Molecular Weight: 0

UniProt: P14151