IL-10 antibody (FineTest®700)

Catalog No. ABIN7675217

This anti-IL-10 antibody is a Rat Monoclonal antibody detecting IL-10 in FACS. Suitable for Mouse.

Quick Overview for IL-10 antibody (FineTest®700) (ABIN7675217)

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-10 antibody is conjugated to FineTest®700

Application: Flow Cytometry (FACS)

Clone: JES5-16E3

Product Details anti-IL-10 Antibody (FineTest®700)

Purpose: FineTest®700 Anti-Mouse IL-10 Antibody

Isotype: IgG2b, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for IL-10

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Alternative Name: IL-10

Background:

Synonyms: CSIF|Cytokine synthesis inhibitory factor|IL-10|Interleukin-10

Background: IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IIL-10 shares over 80 % sequence homology with the Epstein-Barr virus protein BCRFI. IIL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones, inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis, suppresses the delayed type hypersensitivity response, stimulates Th2 cell response (which results in elevated antibody production), and promotes mast cell proliferation in combination with IL-4.

Molecular Weight: 0

Gene ID: 16153

UniProt: P18893

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints