CD44 Standard antibody (FineTest®700)

Catalog No. ABIN7675296

This Mouse Monoclonal antibody specifically detects CD44 Standard in FACS. It exhibits reactivity toward Rat.

Quick Overview for CD44 Standard antibody (FineTest®700) (ABIN7675296)

Target: CD44 Standard (CD44s)

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD44 Standard antibody is conjugated to FineTest®700

Application: Flow Cytometry (FACS)

Clone: OX-49

Product Details anti-CD44 Standard Antibody (FineTest®700)

Purpose: FineTest®700 Anti-Rat CD44H Antibody

Isotype: IgG2a, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for CD44 Standard

Target: CD44 Standard (CD44s)

Alternative Name: CD44H

Background:

Synonyms: CD44sH-CAM|CD44H|Pgp-1

Background: CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.

Molecular Weight: 0

Gene ID: 12505

UniProt: P26051