Interleukin 17a antibody (FineTest®700)

Catalog No. ABIN7675474

The Mouse Monoclonal anti-Interleukin 17a antibody has been validated for FACS. It is suitable to detect Interleukin 17a in samples from Mouse.

Quick Overview for Interleukin 17a antibody (FineTest®700) (ABIN7675474)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Interleukin 17a antibody is conjugated to FineTest®700

Application: Flow Cytometry (FACS)

Clone: 17F3

Product Details anti-Interleukin 17a Antibody (FineTest®700)

Purpose: FineTest®700 Anti-Mouse IL-17A Antibody

Isotype: IgG1, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Alternative Name: IL-17A

Background:

Synonyms: Ctla8|Il17a|Interleukin-17A

Background: The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-17A in vivo.

Molecular Weight: 0

Gene ID: 16171

UniProt: Q62386