MMP16 antibody (PE-Cy5)

Catalog No. ABIN735455

The Rabbit Polyclonal anti-MMP16 antibody has been validated for WB and FACS. It is suitable to detect MMP16 in samples from Human, Mouse, Rat, Cow, Dog, Pig and Chicken.

Quick Overview for MMP16 antibody (PE-Cy5) (ABIN735455)

Target: MMP16 (Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP16 antibody is conjugated to PE-Cy5

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-MMP16 Antibody (PE-Cy5)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MMP-16

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MMP16

Target: MMP16 (Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16))

Alternative Name: MMP-16

Background:

Synonyms: MMP-X2, C8orf57, MT-MMP2, MT-MMP3, MT3-MMP, Matrix metalloproteinase-16, MMP-16, Membrane-type matrix metalloproteinase 3, MT-MMP 3, MTMMP3, Membrane-type-3 matrix metalloproteinase, MT3MMP, MMP16, MMPX2

Background: Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.

Molecular Weight: 55/65kDa

Gene ID: 4325

UniProt: P51512