Netrin 1 antibody (AA 501-604) (HRP)

Catalog No. ABIN735482

The Rabbit Polyclonal anti-Netrin 1 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect Netrin 1 in samples from Mouse and Rat.

Quick Overview for Netrin 1 antibody (AA 501-604) (HRP) (ABIN735482)

Target: Netrin 1 (NTN1)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Netrin 1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Netrin 1 Antibody (HRP)

Binding Specificity: AA 501-604

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NtN1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Netrin 1

Target: Netrin 1 (NTN1)

Alternative Name: Ntn1/Netrin 1

Background:

Synonyms: NTN1L, Netrin-1, Epididymis tissue protein Li 131P, NTN1

Background: Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.

Gene ID: 9423

UniProt: O95631

Pathways: Regulation of Cell Size