Neuroglobin antibody (AA 51-151) (HRP)

Catalog No. ABIN735497

The Rabbit Polyclonal anti-Neuroglobin antibody has been validated for ELISA, IHC (fro) and IHC (p). It is suitable to detect Neuroglobin in samples from Rat.

Quick Overview for Neuroglobin antibody (AA 51-151) (HRP) (ABIN735497)

Target: Neuroglobin (NGB)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuroglobin antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Neuroglobin Antibody (HRP)

Binding Specificity: AA 51-151

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse NGB

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Neuroglobin

Target: Neuroglobin (NGB)

Alternative Name: NGB/neuroglobin

Background:

Synonyms: Neuroglobin, Ngb

Background: Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.

Gene ID: 64242

UniProt: Q9ER97