MRAS antibody (AA 105-208)

Catalog No. ABIN735818

The Rabbit Polyclonal anti-MRAS antibody is suitable to detect MRAS in samples from Rat. It has been validated for WB, ELISA, IF (cc), IF (p), IHC (fro) and IHC (p).

Quick Overview for MRAS antibody (AA 105-208) (ABIN735818)

Target: MRAS (Muscle RAS Oncogene Homolog (MRAS))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRAS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MRAS Antibody

Binding Specificity: AA 105-208

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MRAS

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MRAS

Target: MRAS (Muscle RAS Oncogene Homolog (MRAS))

Alternative Name: M-RAS/Mras

Background:

Synonyms: muscle RAS oncogene homolog precursor, M ras, Muscle and microspikes Ras, Muscle Ras oncogene homologue, R ras3, R-ras3, Ras related protein MRas, Ras related protein RRas3, RRas3, XRas.

Background: MRas is a member of the RAS superfamily of GTP-binding proteins which are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors. MRas participates in reorganisation of actin cytoskeleton. It is also involved in focal adhesion and can activate MAPK signalling.

Gene ID: 22808