MRAS antibody (AA 105-208) (HRP)

Catalog No. ABIN735827

The Rabbit Polyclonal anti-MRAS antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect MRAS in samples from Rat.

Quick Overview for MRAS antibody (AA 105-208) (HRP) (ABIN735827)

Target: MRAS (Muscle RAS Oncogene Homolog (MRAS))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRAS antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MRAS Antibody (HRP)

Binding Specificity: AA 105-208

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MRAS

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MRAS

Target: MRAS (Muscle RAS Oncogene Homolog (MRAS))

Alternative Name: M-RAS/Mras

Background:

Synonyms: muscle RAS oncogene homolog precursor, M ras, Muscle and microspikes Ras, Muscle Ras oncogene homologue, R ras3, R-ras3, Ras related protein MRas, Ras related protein RRas3, RRas3, XRas.

Background: MRas is a member of the RAS superfamily of GTP-binding proteins which are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors. MRas participates in reorganisation of actin cytoskeleton. It is also involved in focal adhesion and can activate MAPK signalling.

Gene ID: 22808