SLC6A4 antibody (AA 401-500) (HRP)

Catalog No. ABIN735992

The Rabbit Polyclonal anti-SLC6A4 antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect SLC6A4 in samples from Human, Rat, Mouse and Chicken.

Quick Overview for SLC6A4 antibody (AA 401-500) (HRP) (ABIN735992)

Target: SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))

Reactivity: Human, Rat, Mouse, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC6A4 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SLC6A4 Antibody (HRP)

Binding Specificity: AA 401-500

Cross-Reactivity: Chicken, Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5-HTT

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SLC6A4

Target: SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))

Alternative Name: SLC6A4/5-HTT

Background:

Synonyms: HTT, 5HTT, OCD1, SERT, 5-HTT, SERT1, hSERT, 5-HTTLPR, Sodium-dependent serotonin transporter, 5HT transporter, Solute carrier family 6 member 4, SLC6A4

Background: Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.

Gene ID: 6532

UniProt: P31645