Ketamine antibody
Quick Overview for Ketamine antibody (ABIN7794723)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Ketamine-(Clone KET-0498)
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Specificity
- Anti-Ketamine (clone KET-0498) is specific for ketamine. Ketamine - 100 % Norketamine - 60 % . Background Ketamine is a nonbarbiturate dissociative anesthetic that has been approved for use in general anesthesia both alone and in combination with other medications. Ketamine's primary mechanism of action involves antagonizing N-methyl-D-aspartate (NMDA) receptors in the brain, leading to dissociation of sensory perceptions and producing analgesic and hallucinogenic effects. Recent research has shown long-lasting antidepressant activity and chronic pain relief likely due to structural brain changes induced by the drug. Ketamine has emerged as a novel and promising treatment for certain psychiatric conditions, such as treatment-resistant depression and post-traumatic stress disorder (PTSD), administered in controlled clinical settings. However, its misuse, particularly in recreational settings, raises concerns due to its dissociative effects and potential for addiction.
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Purification
- This monoclonal antibody is purified by ion exchange chromatography.
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Purity
- >90 % for SDS PAGE
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Isotype
- IgG2a kappa
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Restrictions
- For Research Use only
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Concentration
- 1 μg/mL
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Buffer
- Formulated in 0.015M potassium phosphate buffered saline (0.85 % ), pH 7.2 and contains 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- This purified antibody is stable when stored at 2-8°C. Do not freeze.
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- Ketamine
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Target Type
- Chemical
Target
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