hCG antibody

Catalog No. ABIN7794763

This anti-hCG antibody is a HEK-293 Cells Monoclonal antibody detecting hCG in . Suitable for Human.

Quick Overview for hCG antibody (ABIN7794763)

Target: hCG (Chorionic Gonadotropin (hCG))

Reactivity: Human

Host: HEK-293 Cells

Clonality: Monoclonal

Conjugate: This hCG antibody is un-conjugated

Application: Please inquire

Clone: L521

Product Details anti-hCG Antibody

Purpose: Anti-Human HCG (Clone L521)-Purified No Carrier Protein

Specificity: Mouse Anti-Human Chorionic Gonadotropin (HCG) Beta (Clone L521) recognizes Human Chorionic Gonadotropin (HCG) Beta. Background Human chorionic gonadotropin (hCG) is a hormone produced by cells surrounding a growing embryo, which eventually forms the placenta after implantation1. Its primary function is the maternal recognition of pregnancy, allowing the corpus luteum to secrete progesterone during the first trimester to enrich the uterine lining and sustain the fetus 1. hCG is naturally produced by the syncytiotrophoblast cells of the placenta 1. It is a glycoprotein dimer consisting of an ? subunit identical to other hormones like LH, FSH, and TSH, and a unique ? subunit 4. The genes for the ? and ? subunits are located on different chromosomes 5. The presence of hCG is detected in pregnancy tests due to its elevated levels in pregnant women's urine and blood 1,3. It can also be used to induce ovulation and testosterone production for fertility treatments 1. Historically, hCG was first isolated from the urine of pregnant women in 1928 by Aschheim and Zondek, leading to the development of early pregnancy tests 2. Elevated hCG levels when not pregnant may indicate certain cancers like choriocarcinoma, as some tumors can produce this hormone 1. However, its role in carcinogenesis is unclear.

Purification: Antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.

Purity: >=90 % monomer by analytical SEC and SDS-Page

Immunogen: Purified HCG Beta

Application Details

Restrictions: For Research Use only

Handling

Concentration: 1 μg/mL

Buffer: This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.

Preservative: Without preservative

Storage: 4 °C,-80 °C

Storage Comment: Antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -70°C. Avoid Repeated Freeze Thaw Cycles.

Target Details for hCG

Target: hCG (Chorionic Gonadotropin (hCG))

Alternative Name: HCG