Influenza A Virus Neuraminidase antibody (Internal Region)

Catalog No. ABIN7794997

This anti-Influenza A Virus Neuraminidase antibody is a Rabbit Polyclonal antibody detecting Influenza A Virus Neuraminidase in . Suitable for Avian Influenza Virus.

Quick Overview for Influenza A Virus Neuraminidase antibody (Internal Region) (ABIN7794997)

Target: Influenza A Virus Neuraminidase (NA)

Reactivity: Avian Influenza Virus

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Influenza A Virus Neuraminidase antibody is un-conjugated

Application: Please inquire

Product Details anti-Influenza A Virus Neuraminidase Antibody

Binding Specificity: Internal Region

Purpose: Anti-Avian Influenza Neuraminidase (Intermediate Domain)

Specificity: Rabbit Anti-Avian Influenza Neuraminidase recognizes Avian Influenza Neuraminidase. This polyclonal antibody was purified using affinity chromatography.Background Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA.1 Novel influenza virus strains emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however it is in birds that all subtypes can be found.2 These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong.3 There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low.4 Although it has been known that cleavage site and glycosylation patterns of the HA protein play important roles in determining the pathogenicity of H5 avian influenza viruses, it has only recently been shown that an additional glycosylation site within the globular head of the NA protein also contributes to the high virulence of the H5N1 virus.

Application Details

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/mL

Buffer: This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02 % sodium azide as a preservative.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Target Details for Influenza A Virus Neuraminidase

Target: Influenza A Virus Neuraminidase (NA)

Alternative Name: Avian Influenza Neuraminidase

Target Type: Influenza Protein