The Humanized Monoclonal anti-CD38 (Isatuximab Biosimilar) antibody (ABIN7795129) specifically detects CD38 (Isatuximab Biosimilar) in FACS and in vivo.
The antibody is reactive with Human samples.
Quick Overview for Recombinant CD38 (Isatuximab Biosimilar) antibody (ABIN7795129)
Target
CD38 (Isatuximab Biosimilar)
Antibody Type
Recombinant Antibody
Reactivity
Human
Host
Humanized
Clonality
Monoclonal
Conjugate
This CD38 (Isatuximab Biosimilar) antibody is un-conjugated
Application
Flow Cytometry (FACS), In vivo Studies (in vivo)
Grade
Research Grade
Expression System
Mammalian cells
Purpose
Isatuximab Biosimilar, CD38 Monoclonal Antibody
Characteristics
Isatuximab Biosimilar uses the same protein sequences as the therapeutic antibody isatuximab. Isatuximab is a humanized, IgG1-derived monoclonal antibody (mAb) produced from a Chinese hamster ovary (CHO) cell line. Structurally, isatuximab is comprised of two identical immunoglobulin kappa light chains and two identical immunoglobulin gamma heavy chains. It is a cytolytic antibody targeted against CD38, a glycoprotein found on the surface of some immune cells that is highly expressed by malignant plasma cells in multiple myeloma. Along with daratumumab, another anti-CD38 monoclonal antibody, isatuximab constitutes a novel treatment modality for patients with difficult-to-treat multiple myeloma.