Recombinant CD8 alpha antibody

Catalog No. ABIN7795361

This Mouse Monoclonal antibody specifically detects CD8 alpha in ELISA, Func, Neut and IGA. It exhibits reactivity toward Human.

Quick Overview for Recombinant CD8 alpha antibody (ABIN7795361)

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD8 alpha antibody is un-conjugated

Application: ELISA, Functional Studies (Func), Neutralization (Neut), Immunogenicity Assay (IGA)

Grade: In vivo Grade

Clone: OKT8

Product Details anti-CD8 alpha Antibody

Expression System: Mammalian cells

Purpose: In vivo Grade Recombinant Anti-human CD8a Monoclonal Antibody (Clone: OKT8), Mouse IgG2a Kappa

Characteristics: The recombinant OKT8 antibody binds to the human CD8 protein (cluster of differentiation 8), a type I transmembrane glycoprotein and the co-receptor for the T-cell receptor (TCR). Along with the TCR, the CD8 co-receptor plays a role in T cell signaling and aiding with cytotoxic T cell-antigen interactions. The CD8 protein is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells, cortical thymocytes, and dendritic cells. The CD8 Molecule is a marker for cytotoxic T cell population.

Purification: Protein A or G affinity column

Purity: >95 % by reducing SDS-PAGE

Endotoxin Level: < 1 EU per 1 mg of the protein by the LAL method

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: > 3 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Target Details for CD8 alpha

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Alternative Name: CD8a

Pathways: TCR Signaling