Recombinant PD-L1 antibody

Catalog No. ABIN7795508

This Human Monoclonal antibody specifically detects PD-L1 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for Recombinant PD-L1 antibody (ABIN7795508)

Target: PD-L1 (CD274 (PD-L1))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Human

Clonality: Monoclonal

Conjugate: This PD-L1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 10F-9G2

Product Details anti-PD-L1 Antibody

Expression System: Mammalian cells

Purpose: Recombinant Anti-mouse PD-L1 Monoclonal Antibody (Clone: 10F.9G2.1), Human IgG1 Fc Silent Kappa

Characteristics: The rat anti-mouse PD-L1 monoclonal antibody 10F.9G2 (rat IgG2b kappa) reacts with the mouse PD-L1 protein (programmed death ligand-1, B7-H1 or CD274), a member of the B7 family of the Ig superfamily. PD-1 has two ligands, PD-L1 and PD-L2. It has been shown that in mouse models of melanoma, tumor growth can be transiently arrested via treatment with the anti-mouse PD-1 and anti-mouse PD-L1 antibodies which block the interaction between the PD-L1 protein and its receptor PD-1 protein. The 10F.9G2 monoclonal antibody blocks the binding of the mouse PD-L1 protein to the mouse PD-1 protein. Our recombinant 10F.9G2 antibodies have a part (variable regions) or complete amino acid sequences of the rat anti-mouse PD L1 monoclonal antibody (hybridoma clone name or number: 10F.9G2).

Purification: Protein A or G affinity column

Purity: >95 % by reducing SDS-PAGE

Isotype: Fc Silenced, IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: > 3 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Target Details for PD-L1

Target: PD-L1 (CD274 (PD-L1))

Alternative Name: PD-L1

Pathways: Cancer Immune Checkpoints