PAX8 antibody

Catalog No. ABIN7795602

The Mouse Monoclonal anti-PAX8 antibody has been validated for IHC and ICC. It is suitable to detect PAX8 in samples from Human.

Quick Overview for PAX8 antibody (ABIN7795602)

Target: PAX8 (Paired Box 8 (PAX8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAX8 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: BC12

Product Details anti-PAX8 Antibody

Purpose: Mouse anti-PAX8 Monoclonal Antibody [BC12]

Purification: Purified

Immunogen: Human PAX8

Isotype: IgG1

Application Details

Application Notes: ICC,1100 to 1500. Epitope retrieval using pressure cooker with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval, using pressure cooker with citrate buffer pH 6.0 is recommended for FFPE tissue sections. ,WB,11000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 50 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for PAX8

Target: PAX8 (Paired Box 8 (PAX8))

Alternative Name: PAX8

Background: PAX8 is a member of the paired box (PAX) family of transcription factors. PAX8 is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. [taken from NCBI Entrez Gene (Gene ID: 7849)].

Gene ID: 7849

UniProt: Q06710

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation