Recombinant CD70 antibody (AA 50-193)

Catalog No. ABIN7795664

This Rabbit Monoclonal antibody specifically detects CD70 in WB, IHC and ICC. It exhibits reactivity toward Human.

Quick Overview for Recombinant CD70 antibody (AA 50-193) (ABIN7795664)

Target: CD70 (CD70 Molecule (CD70))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD70 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: BLR266L

Product Details anti-CD70 Antibody

Binding Specificity: AA 50-193

Purpose: Rabbit anti-CD70 Recombinant Monoclonal Antibody [BLR266L] - BSA-Free

Purification: Purified

Immunogen: Residues 50-193 (ECD)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: CD70

Background: CD70, a cytokine that belongs to the tumor necrosis factor (TNF) ligand family, is a ligand for TNFRSF27/CD27. CD70 is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. CD70 also plays a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. [taken from NCBI Entrez Gene (Gene ID: 970)].

Gene ID: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints