Recombinant FOXP3 antibody (AA 275-325)

Catalog No. ABIN7795682

This Rabbit Monoclonal antibody specifically detects FOXP3 in WB, FACS and IP. It exhibits reactivity toward Human.

Quick Overview for Recombinant FOXP3 antibody (AA 275-325) (ABIN7795682)

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FOXP3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: BLR282M

Product Details anti-FOXP3 Antibody

Binding Specificity: AA 275-325

Purpose: Rabbit anti-FOXP3 Recombinant Monoclonal Antibody [BLR282M]

Purification: Purified

Immunogen: Between 275 and 325

Isotype: IgG

Application Details

Application Notes: IP,6 μL/mg lysate,WB,11000,Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 0.5 μL per 1 x 10^6 cells.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for FOXP3

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Alternative Name: FOXP3

Background: FOXP3 is a transcriptional regulator which is crucial for the development and inhibitory function of regulatory T-cells (Treg). It plays an essential role in maintaining homeostasis of the immune system by allowing the acquisition of full suppressive function and stability of the Treg lineage, and by directly modulating the expansion and function of conventional T-cells. FOXP3 can act either as a transcriptional repressor or a transcriptional activator depending on its interactions with other transcription factors, histone acetylases and deacetylases.  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BZS1].

Gene ID: 50943

UniProt: Q9BZS1

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation