Recombinant Lamin B1 antibody (AA 450-500)

Catalog No. ABIN7795809

The Rabbit Monoclonal anti-Lamin B1 antibody has been validated for WB, IHC and ICC. It is suitable to detect Lamin B1 in samples from Human and Mouse.

Quick Overview for Recombinant Lamin B1 antibody (AA 450-500) (ABIN7795809)

Target: Lamin B1 (LMNB1)

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Lamin B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: BLR368N

Product Details anti-Lamin B1 Antibody

Binding Specificity: AA 450-500

Purpose: Rabbit anti-Lamin B1 Recombinant Monoclonal Antibody [BLR368N]

Purification: Purified

Immunogen: between 450 and 500

Isotype: IgG

Application Details

Application Notes: ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,WB,11,000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for Lamin B1

Target: Lamin B1 (LMNB1)

Alternative Name: Lamin B1

Background: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin B1 is one of the two B-type lamin proteins. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [taken from NCBI Entrez Gene (Gene ID: 4001)].

Gene ID: 4001

UniProt: P20700

Pathways: Apoptosis, Caspase Cascade in Apoptosis