Fibrillin 1 antibody (AA 401-500) (HRP)

Catalog No. ABIN738510

This anti-Fibrillin 1 antibody is a Rabbit Polyclonal antibody detecting Fibrillin 1 in ELISA, IHC (p) and IHC (fro). Suitable for Human and Rat.

Quick Overview for Fibrillin 1 antibody (AA 401-500) (HRP) (ABIN738510)

Target: Fibrillin 1 (FBN1)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibrillin 1 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Fibrillin 1 Antibody (HRP)

Binding Specificity: AA 401-500

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FBN1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Fibrillin 1

Target: Fibrillin 1 (FBN1)

Alternative Name: Fibrillin 1

Background:

Synonyms: FBN, SGS, WMS, MASS, MFS1, OCTD, SSKS, WMS2, ACMICD, ECTOL1, GPHYSD2, Fibrillin-1, FBN1

Background: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.

Gene ID: 2200

UniProt: P35555

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome