GRM2 antibody (AA 801-872) (Biotin)

Catalog No. ABIN738563

The Rabbit Polyclonal anti-GRM2 antibody has been validated for ELISA, WB, IHC (p) and IHC (fro). It is suitable to detect GRM2 in samples from Rat.

Quick Overview for GRM2 antibody (AA 801-872) (Biotin) (ABIN738563)

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRM2 antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GRM2 Antibody (Biotin)

Binding Specificity: AA 801-872

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GRM2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GRM2

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Alternative Name: Metabotropic glutamate receptor 2

Background:

Synonyms: GLUR2, mGlu2, GPRC1B, MGLUR2, Metabotropic glutamate receptor 2, GRM2

Background: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

Gene ID: 2912

UniProt: Q14416

Pathways: cAMP Metabolic Process, Dicarboxylic Acid Transport