IL-17 antibody (AA 85-150)

Catalog No. ABIN738891

This anti-IL-17 antibody is a Rabbit Polyclonal antibody detecting IL-17 in WB, ELISA, FACS, IF (cc), IF (p), IHC (p) and IHC (fro). Suitable for Human, Mouse and Rat. This Primary Antibody has been cited in 8+ publications.

Quick Overview for IL-17 antibody (AA 85-150) (ABIN738891)

Target: IL-17 (IL17) (Interleukin 17 (IL17))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-IL-17 Antibody

Binding Specificity: AA 85-150

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat IL-17

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-IL-17 antibody (ABIN738891)

Yang, Liu, Zhang, Hu, Chen, Wang, Yin, Li, Qi: "Effect of IL-17 in the development of colon cancer in mice." in: Oncology letters, Vol. 12, Issue 6, pp. 4929-4936, (2017) (PubMed).

Chen, Qu, Li, Ye, Zhang, Qin, Fan: "Effects of 1,25-dihydroxyvitamin D3 in an ovalbumin-induced allergic rhinitis model." in: International immunopharmacology, Vol. 47, pp. 182-189, (2017) (PubMed).

Liao, Hu, Guo, Zhang, Xu, Jiang: "Promoting effects of IL‑23 on myocardial ischemia and reperfusion are associated with increased expression of IL‑17A and upregulation of the JAK2‑STAT3 signaling pathway." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 9309-9316, (2017) (PubMed).

Venkatasubramanian, Tripathi, Tucker, Paidipally, Cheekatla, Welch, Raghunath, Jeffers, Tvinnereim, Schechter, Andrade, Mackman, Idell, Vankayalapati: "Tissue factor expression by myeloid cells contributes to protective immune response against Mycobacterium tuberculosis infection." in: European journal of immunology, Vol. 46, Issue 2, pp. 464-79, (2016) (PubMed).

Yi, Zhang, Hu, Li, Jiang, Xu, Lu, Liao, Ma, Li, Wang: "Vagus nerve stimulation attenuates myocardial ischemia/reperfusion injury by inhibiting the expression of interleukin-17A." in: Experimental and therapeutic medicine, Vol. 11, Issue 1, pp. 171-176, (2016) (PubMed).

Yang, Gao, Shi, Zhou, Qu, Xu, Shan, Teng: "Effect of iodine excess on Th1, Th2, Th17, and Treg cell subpopulations in the thyroid of NOD.H-2h4 mice." in: Biological trace element research, Vol. 159, Issue 1-3, pp. 288-96, (2014) (PubMed).

Ishida, Harada, Fukuda, Taguchi, Yagita, Fukushima: "Inhibition of very late antigen-4 and leukocyte function-associated antigen-1 in experimental autoimmune uveoretinitis." in: Clinical immunology (Orlando, Fla.), Vol. 153, Issue 1, pp. 136-44, (2014) (PubMed).

Target Details for IL-17

Target: IL-17 (IL17) (Interleukin 17 (IL17))

Alternative Name: IL-17

Background:

Synonyms: IL17, CTLA8, IL-17, IL-17A, Interleukin-17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8, IL17A

Background: Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.

Gene ID: 301289

UniProt: Q61453