MPZ antibody (AA 175-248)

Catalog No. ABIN738954

Cited in 5+ publications. The Rabbit Polyclonal anti-MPZ antibody (ABIN738954) specifically detects MPZ in WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). The antibody is reactive with Rat, Mouse and Dog samples.

Quick Overview for MPZ antibody (AA 175-248) (ABIN738954)

Target: MPZ (Myelin Protein Zero (MPZ))

Reactivity: Rat, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPZ antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MPZ Antibody

Binding Specificity: AA 175-248

Specificity: This antibody will recongize both isforms

Cross-Reactivity: Dog, Mouse, Rat

Predicted Reactivity: Human,Cow,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Myelin Protein Zero

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-MPZ antibody (ABIN738954)

Röhr, Halfter, Schulz, Young, Gess: "Sodium-dependent Vitamin C transporter 2 deficiency impairs myelination and remyelination after injury: Roles of collagen and demethylation." in: Glia, Vol. 65, Issue 7, pp. 1186-1200, (2017) (PubMed).

Schulz, Büttner, Hagel, Baader, Kluwe, Salamon, Mautner, Mindos, Parkinson, Gehlhausen, Clapp, Morrison: "The importance of nerve microenvironment for schwannoma development." in: Acta neuropathologica, Vol. 132, Issue 2, pp. 289-307, (2016) (PubMed).

Chitose, Sato, Fukahori, Sueyoshi, Kurita, Umeno: "Recurrent laryngeal nerve regeneration using an oriented collagen scaffold containing Schwann cells." in: The Laryngoscope, Vol. 127, Issue 7, pp. 1622-1627, (2016) (PubMed).

Schulz, Kyselyova, Baader, Jung, Zoch, Mautner, Hagel, Morrison: "Neuronal merlin influences ERBB2 receptor expression on Schwann cells through neuregulin 1 type III signalling." in: Brain : a journal of neurology, Vol. 137, Issue Pt 2, pp. 420-32, (2014) (PubMed).

Li, Ma, Liu, Guo, Li, Li, Han, Wang, Wu: "Relationship between neural alteration and perineural invasion in pancreatic cancer patients with hyperglycemia." in: PLoS ONE, Vol. 6, Issue 2, pp. e17385, (2011) (PubMed).

Target Details for MPZ

Target: MPZ (Myelin Protein Zero (MPZ))

Alternative Name: Myelin Protein Zero

Background:

Synonyms: P, CHM, DSS, MPP, CMT1, CMT1B, CMT2I, CMT2J, CMT4E, CMTDI3, CMTDID, HMSNIB, Myelin protein P, Myelin peripheral protein, Myelin protein zero, MPZ

Background: Creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae.

Gene ID: 4359

UniProt: P25189