MFN2 antibody (Cytosolic, N-Term) (FL490)

Catalog No. ABIN7823134

This Mouse Monoclonal antibody specifically detects MFN2 in IHC and ICC. It exhibits reactivity toward Mouse.

Quick Overview for MFN2 antibody (Cytosolic, N-Term) (FL490) (ABIN7823134)

Target: MFN2 (Mitofusin 2 (MFN2))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This MFN2 antibody is conjugated to FL490

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Grade: KO Validated

Clone: N153-5

Product Details anti-MFN2 Antibody (FL490)

Binding Specificity: AA 370-600, Cytosolic, N-Term

Purpose: Anti-Mitofusin-2 Antibody FL490 Conjugate

Specificity: No off-targets reported for Mitofusin-1

Cross-Reactivity: Rat

Characteristics: Our Anti-Mitofusin-2 mouse monoclonal primary antibody is produced in-house from hybridoma clone N153/5. It is KO validated, detects mouse and rat Mitofusin-2, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Purity: Purified mAbs are >90 % specific antibody.

Immunogen: Fusion protein amino acids 370-600 (cytoplasmic N-terminus) of mouse Mitofusin-2 (accession number Q80U63) produced recombinantly in E. Coli

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: For maximum recovery of product, centrifuge the vial prior to removing the cap.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C.

Expiry Date: 12 months

Target Details for MFN2

Target: MFN2 (Mitofusin 2 (MFN2))

Alternative Name: Mitofusin-2

Background:

Synonyms: Mitofusin-2 (EC 3.6.5.-) (Hypertension-related protein 1) (Mitochondrial assembly regulatory factor) (HSG protein) (Transmembrane GTPase MFN2)

Description Logic: Our Anti-Mitofusin-2 mouse monoclonal primary antibody is produced from hybridoma clone N153/5. It is KO validated, detects mouse and rat Mitofusin-2, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Gene Name Alternatives: Mfn2 Kiaa0214 Marf

Molecular Weight: 90 kDa

UniProt: Q80U63

Pathways: Skeletal Muscle Fiber Development