Frataxin antibody (C-Term) (FL650)

Catalog No. ABIN7823302

This Mouse Monoclonal antibody specifically detects Frataxin in ICC. It exhibits reactivity toward Human.

Quick Overview for Frataxin antibody (C-Term) (FL650) (ABIN7823302)

Target: Frataxin (FXN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Frataxin antibody is conjugated to FL650

Application: Immunocytochemistry (ICC)

Clone: N191-7

Product Details anti-Frataxin Antibody (FL650)

Binding Specificity: AA 81-210, C-Term

Purpose: Anti-Frataxin Antibody FL650 Conjugate

Specificity: No off-targets reported

Characteristics: Our Anti-Frataxin mouse monoclonal primary antibody is produced in-house from hybridoma clone N191/7. It detects human Frataxin, and is purified by protein a chromatography. It is great for use in ICC.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Purity: Purified mAbs are >90 % specific antibody.

Immunogen: Fusion protein amino acids 81-210 (C-terminus) of human Frataxin (accession number Q16595) produced recombinantly in E. Coli

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: For maximum recovery of product, centrifuge the vial prior to removing the cap.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C.

Expiry Date: 12 months

Target Details for Frataxin

Target: Frataxin (FXN)

Alternative Name: Frataxin

Background:

Synonyms: Frataxin, mitochondrial (EC 1.16.3.1) (Friedreich ataxia protein) (Fxn) [Cleaved into: Frataxin intermediate form (i-FXN), Frataxin(56-210) (m56-FXN), Frataxin(78-210) (d-FXN) (m78-FXN), Frataxin mature form (Frataxin(81-210)) (m81-FXN)]

Description Logic: Our Anti-Frataxin mouse monoclonal primary antibody is produced from hybridoma clone N191/7. It detects human Frataxin, and is purified by protein a chromatography. It is great for use in ICC.

Gene Name Alternatives: FXN FRDA X25

Molecular Weight: 25 kDa

UniProt: Q16595

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size