Neuregulin antibody (Extracellular, Heparin Binding Domain, N-Term) (FL594)

Catalog No. ABIN7823366

The Mouse Monoclonal anti-Neuregulin antibody is suitable to detect Neuregulin in samples from Human. It has been validated for ICC.

Quick Overview for Neuregulin antibody (Extracellular, Heparin Binding Domain, N-Term) (FL594) (ABIN7823366)

Target: Neuregulin (LOC101828962) (Pro-Neuregulin-1, Membrane-Bound Isoform-Like (LOC101828962))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Neuregulin antibody is conjugated to FL594

Application: Immunocytochemistry (ICC)

Clone: N120A-9

Product Details anti-Neuregulin Antibody (FL594)

Binding Specificity: AA 14-117, Extracellular, Heparin Binding Domain, N-Term

Purpose: Anti-Neuregulin-HBD (Heparin Binding Domain, Type I/II) Antibody FL594 Conjugate

Specificity: No off-targets reported

Characteristics: Our Anti-Neuregulin-HBD (Heparin binding domain, Type I/II) mouse monoclonal primary antibody is produced in-house from hybridoma clone N120A/9. It detects human Neuregulin-HBD (Heparin binding domain, Type I/II), and is purified by protein a chromatography. It is great for use in ICC.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Purity: Purified mAbs are >90 % specific antibody.

Immunogen: Fusion protein amino acids 14-117 (extracellular N-terminus) of human Neuregulin-1 (accession number Q02297) produced recombinantly in E. Coli

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: For maximum recovery of product, centrifuge the vial prior to removing the cap.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C.

Expiry Date: 12 months

Target Details for Neuregulin

Target: Neuregulin (LOC101828962) (Pro-Neuregulin-1, Membrane-Bound Isoform-Like (LOC101828962))

Alternative Name: Neuregulin

Background:

Synonyms: Pro-neuregulin-1, membrane-bound isoform (Pro-NRG1) [Cleaved into: Neuregulin-1 (Acetylcholine receptor-inducing activity) (ARIA) (Breast cancer cell differentiation factor p45) (Glial growth factor) (Heregulin) (HRG) (Neu differentiation factor) (Sensory and motor neuron-derived factor)]

Description Logic: Our Anti-Neuregulin-HBD (Heparin binding domain, Type I/II) mouse monoclonal primary antibody is produced from hybridoma clone N120A/9. It detects human Neuregulin-HBD (Heparin binding domain, Type I/II), and is purified by protein a chromatography. It is great for use in ICC.

Gene Name Alternatives: NRG1 GGF HGL HRGA NDF SMDF

Molecular Weight: None Reported

UniProt: Q02297