ADRA2C antibody (C-Term, Cytosolic) (FL650)

Catalog No. ABIN7823647

This Mouse Monoclonal antibody specifically detects ADRA2C in ICC. It exhibits reactivity toward Human.

Quick Overview for ADRA2C antibody (C-Term, Cytosolic) (FL650) (ABIN7823647)

Target: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADRA2C antibody is conjugated to FL650

Application: Immunocytochemistry (ICC)

Grade: KO Validated

Clone: N330A-51

Product Details anti-ADRA2C Antibody (FL650)

Binding Specificity: AA 442-462, C-Term, Cytosolic

Purpose: Anti-Alpha-2C Adrenergic Receptor Antibody FL650 Conjugate

Sequence: QDFRRSFKHI LFRRRRRGFR Q

Specificity: No off-targets reported for other adrenergic receptors (based on KO validation results)

Cross-Reactivity: Mouse

Characteristics: Our Anti-Alpha-2C adrenergic receptor mouse monoclonal primary antibody is produced in-house from hybridoma clone N330A/51. It is KO validated, detects human and mouse Alpha-2C adrenergic receptor, and is purified by protein a chromatography. It is great for use in ICC.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Purity: Purified mAbs are >90 % specific antibody.

Immunogen: Synthetic peptide amino acids 442-462 (QDFRRSFKHILFRRRRRGFRQ, cytoplasmic C-terminus) of human Alpha-2C adrenergic receptor (accession number P18825)

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: For maximum recovery of product, centrifuge the vial prior to removing the cap.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C.

Expiry Date: 12 months

Target Details for ADRA2C

Target: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Alternative Name: Alpha-2C adrenergic receptor

Background:

Synonyms: Alpha-2C adrenergic receptor (Alpha-2 adrenergic receptor subtype C4) (Alpha-2C adrenoreceptor) (Alpha-2C adrenoceptor) (Alpha-2CAR)

Description Logic: Our Anti-Alpha-2C adrenergic receptor mouse monoclonal primary antibody is produced from hybridoma clone N330A/51. It is KO validated, detects human and mouse Alpha-2C adrenergic receptor, and is purified by protein a chromatography. It is great for use in ICC.

Gene Name Alternatives: ADRA2C ADRA2L2 ADRA2RL2

Molecular Weight: 50 kDa and larger (possibly due to dimerization)

UniProt: P18825

Pathways: EGFR Signaling Pathway, cAMP Metabolic Process