KCNN2 antibody (C-Term, Cytosolic) (FL650)

Catalog No. ABIN7823972

The Mouse Monoclonal anti-KCNN2 antibody is suitable to detect KCNN2 in samples from Rat. It has been validated for IHC and ICC.

Quick Overview for KCNN2 antibody (C-Term, Cytosolic) (FL650) (ABIN7823972)

Target: KCNN2 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This KCNN2 antibody is conjugated to FL650

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: K78-29

Product Details anti-KCNN2 Antibody (FL650)

Binding Specificity: AA 546-562, C-Term, Cytosolic

Purpose: Anti-SK2 potassium channel Antibody FL650 Conjugate

Sequence: ENYDKHVTYN AERSRSS

Specificity: No off-targets reported for other SK channels

Cross-Reactivity: Human, Mouse

Characteristics: Our Anti-SK2 potassium channel mouse monoclonal primary antibody is produced in-house from hybridoma clone K78/29. It detects human, mouse, and rat SK2 potassium channel, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Purity: Purified mAbs are >90 % specific antibody.

Immunogen: Synthetic peptide amino acids 546-562 (ENYDKHVTYNAERSRSS, cytoplasmic C-terminus) of rat SK2 (accession number P70604)

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: For maximum recovery of product, centrifuge the vial prior to removing the cap.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C.

Expiry Date: 12 months

Target Details for KCNN2

Target: KCNN2 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2))

Alternative Name: SK2

Background:

Synonyms: Small conductance calcium-activated potassium channel protein 2 (SK2) (SKCa 2) (SKCa2) (KCa2.2)

Description Logic: Our Anti-SK2 potassium channel mouse monoclonal primary antibody is produced from hybridoma clone K78/29. It detects human, mouse, and rat SK2 potassium channel, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Gene Name Alternatives: Kcnn2

Molecular Weight: 50-80 kDa (and larger due to isoforms and dimerization/aggregation)

UniProt: P70604