Myoferlin antibody (AA 175-2003)
Quick Overview for Myoferlin antibody (AA 175-2003) (ABIN7825563)
Target
See all Myoferlin (MYOF) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 175-2003
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Purpose
- Anti-MYOF Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins
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Characteristics
- Anti-MYOF Antibody catalog # A04580-1. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human MYOF recombinant protein (Position: E175-E2003). Human MYOF shares 93.9% amino acid (aa) sequence identity with mouse MYOF.
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Isotype
- IgG
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Application Notes
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Myoferlin (MYOF)
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Alternative Name
- MYOF
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Background
- Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.
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Molecular Weight
- 250 kDa
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Gene ID
- 26509
Target
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