Anti-MTMR3 Antibody catalog # A05937-1. Tested in WB, IHC, IF, ICC, Flow Cytometry, ELISA applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
Purification
Immunogen affinity purified.
Immunogen
E.coli-derived human MTMR3 recombinant protein (Position: M1-E1074).
MTMR3
Reactivity: Human
WB
Host: Mouse
Polyclonal
unconjugated
Application Notes
Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry, 2-5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Target
MTMR3
(Myotubularin Related Protein 3 (MTMR3))
Alternative Name
MTMR3
Background
This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.