Recombinant KDM6A antibody (Center)

Catalog No. ABIN7826128

This Rabbit Monoclonal antibody specifically detects KDM6A in IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant KDM6A antibody (Center) (ABIN7826128)

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This KDM6A antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: HMV311

Product Details anti-KDM6A Antibody

Binding Specificity: Center

Purpose: KDM6A antibody (HMV311)

Immunogen: Recombinant protein encompassing a sequence within the center region of human KDM6A. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:200

Comment:

Positive Control: Testis: A strong KDM6A staining should be seen in Sertoli cells, Leydig cells and in immature cells of the spermatogenesis (spermatogonia).

Product Description/Background: KDM6A antibody validated for immunohistochemistry on 76 different Normal Tissues

Negative Control: Testis: KDM6A staining must be absent in mature cells of the spermatogenesis (spermatocytes, spermatids).

Protocol: Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121 °C in pH 7,8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:100 at 37 °C for 60 minutes.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non- hazardous. No MSD required.

Expiry Date: 24 months

Target Details for KDM6A

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Alternative Name: KDM6A

Background: Gene Alias: lysine demethylase 6A , KABUK2 , UTX , bA386N14.2

UniProt: O15550

Pathways: Tube Formation, Warburg Effect