Recombinant alpha Actinin 4 antibody

Catalog No. ABIN7827997

This Rabbit Monoclonal antibody specifically detects alpha Actinin 4 in WB, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for Recombinant alpha Actinin 4 antibody (ABIN7827997)

Target: alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This alpha Actinin 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: A128

Product Details anti-alpha Actinin 4 Antibody

Purpose: Recombinant alpha Actinin 4 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human Actinin 4 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for alpha Actinin 4

Target: alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

Alternative Name: alpha Actinin 4

Background: ACTN,Non-muscle alpha-actinin,ACTININ,ACTN4,ACTININ-4,FSGS,FSGS1,Non-muscle alpha-actinin 4,actinin 4,Actinin alpha 4,actinin4,ACTN 4,Alpha-actinin-4,DKFZp686K23158,F actin cross linking protein,F-actin cross-linking protein,Focal segmental glomerulosclerosis 1,FSGS 1,Non muscle alpha actinin 4,F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions. May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 100 kDa

Observed MW: 110 kDa The actual band is not consistent with the expectation.

UniProt: O43707

Pathways: Proton Transport