Recombinant CD79a antibody

Catalog No. ABIN7828036

This Rabbit Monoclonal antibody specifically detects CD79a in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant CD79a antibody (ABIN7828036)

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD79a antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A181

Product Details anti-CD79a Antibody

Purpose: Recombinant CD79a Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human CD79a fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:5000,IHC 1:200-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD79a

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Alternative Name: CD79a

Background: CD79A;IGA;MB-1;CD79a molecule;CD79A antigen;MB1;MB1;Ig&alpha,Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 25 kDa

Observed MW: 44-48 kDa The actual band is not consistent with the expectation.

UniProt: P11912

Pathways: BCR Signaling