Recombinant BCR antibody

Catalog No. ABIN7828047

The Rabbit Monoclonal anti-BCR antibody (Clone A591) (ABIN7828047) specifically detects BCR in WB and IHC. The antibody is reactive with Human and Rat samples.

Quick Overview for Recombinant BCR antibody (ABIN7828047)

Target: BCR (Breakpoint Cluster Region (BCR))

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BCR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A591

Product Details anti-BCR Antibody

Purpose: Recombinant Bcr Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human Bcr fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for BCR

Target: BCR (Breakpoint Cluster Region (BCR))

Alternative Name: Bcr

Background: Renal carcinoma antigen NY-REN,BCR,ALL,BCR1,CML,D22S11,D22S662,PHL,Breakpoint cluster region,Renal carcinoma antigen NY-REN-26,bcr,BCR1,Breakpoint cluster region,CML,D22S11,D22S662,PHL,Renal carcinoma antigen NY-REN-26,Break point cluster region protein (Bcr) is encoded by the Bcr gene. The Bcr gene, mapping on chromosome22, was orginally identified by its presence in the chimeric Bcr-Abl oncogene. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine / threonine kinase activity and is a GTPase-activating protein for RAC1 and CDC42. A chromosomal aberration involving BCR has been found in patients with chronic myeloid leukemia. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 160 kDa

Observed MW: 160 kDa

UniProt: P11274

Pathways: Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling