Recombinant Caldesmon antibody

Catalog No. ABIN7828057

This Rabbit Monoclonal antibody specifically detects Caldesmon in WB, IHC and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Recombinant Caldesmon antibody (ABIN7828057)

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Caldesmon antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: A147

Product Details anti-Caldesmon Antibody

Purpose: Recombinant Caldesmon/CDM Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human Caldesmon/CDM fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:200-1:1000,IF 1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Caldesmon

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Alternative Name: Caldesmon/CDM

Background: NAG,MGC,CALD1,CDM,H-CAD,HCAD,L-CAD,LCAD,NAG22,caldesmon,CALD 1,Caldesmon 1,Caldesmon 1 Isoform 1,Caldesmon 1 Isoform 2,Caldesmon 1 Isoform 3,Caldesmon 1 Isoform 4,Caldesmon 1 Isoform 5,Caldesmon1,H CAD,L CAD,MGC21352,CAD,CAD,CALD 1,CALD1,CALD1,Caldesmon 1,Caldesmon 1 Isoform 1,Caldesmon 1 Isoform 2,Caldesmon 1 Isoform 3,Caldesmon 1 Isoform 4,Caldesmon 1 Isoform 5,Caldesmon,Caldesmon1,CDM,H CAD,HCAD,L CAD,LCAD,MGC21352,NAG22,Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also plays an essential role during cellular mitosis and receptor capping. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 93 kDa

Observed MW: 75 kDa The actual band is not consistent with the expectation.

UniProt: Q05682

Pathways: Myometrial Relaxation and Contraction