Recombinant Cathepsin B antibody

Catalog No. ABIN7828071

The Rabbit Monoclonal anti-Cathepsin B antibody (Clone A464) (ABIN7828071) specifically detects Cathepsin B in WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant Cathepsin B antibody (ABIN7828071)

Target: Cathepsin B (CTSB)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Cathepsin B antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A464

Product Details anti-Cathepsin B Antibody

Purpose: Recombinant Cathepsin B Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human Cathepsin B fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:5000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Cathepsin B

Target: Cathepsin B (CTSB)

Alternative Name: Cathepsin B

Background: APPS,CPSB,Cathepsin B,CTSB,APP Secretase,CathepsinB,CATB,Cathepsin B1,cysteine protease,Amyloid precursor protein secretase,Cathepsin B heavy chain,OTTHUMP00000116009,OTTHUMP00000229510,OTTHUMP00000229511,OTTHUMP00000229512,OTTHUMP00000229514,OTTHUMP00000229515,OTTHUMP00000229516,Preprocathepsin B,Cathepsin B is a member of the C1 family of peptidases. This protein is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease. Overexpression of Cathepsin B has been associated with esophageal adenocarcinoma and other tumors. Both Cathepsin B and Cathepsin L are involved in the cleavage of the spike protein from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) upon its entry to the human host cell. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 38 kDa

Observed MW: 38 kDa

UniProt: P07858

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades