Recombinant PD-L1 antibody

Catalog No. ABIN7828077

The Rabbit Monoclonal anti-PD-L1 antibody (Clone A326) (ABIN7828077) specifically detects PD-L1 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant PD-L1 antibody (ABIN7828077)

Target: PD-L1 (CD274 (PD-L1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PD-L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A326

Product Details anti-PD-L1 Antibody

Purpose: Recombinant PD-L1 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human PD-L1 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000,IHC 1:200-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for PD-L1

Target: PD-L1 (CD274 (PD-L1))

Alternative Name: PD-L1

Background: PDL,B7H,PD-L,PD1L,Programmed cell death 1 ligand,PDCD1L,PDCD1LG,B7-H,B7H1,PDL1,PD-L1,PDCD1L1,PDCD1LG1,CD274,B7-H1,B7 homolog 1,CD274 Molecule,PDCD1 ligand 1,Programmed death ligand 1,PD1L1,Programmed cell death 1 ligand 1,PDL1,PD-L1,B7-H,B7H1,CD274 Molecule,PDCD1L1,PDCD1LG1,B7 H,B7 H1,CD 274,CD274 antigen,MGC142294,MGC142296,OTTHUMP00000021029,PD L1,PDL 1,RGD1566211,PD-1 is an immunoinhibitory receptor expressed by activated T cells, B cells, and myeloid cells. Engagement of PD-1 by PD-L1 leads to the inhibition of T cell receptor-mediated lymphocyte proliferation and cytokine secretion. In addition, PD-1 signaling can inhibit at least suboptimal levels of CD28-mediated costimulation. PD-L1 is expressed by antigen-presenting cells, including human peripheral blood monocytes stimulated with interferong, and activated human and murine dendritic cells. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 33 kDa

Observed MW: 50 kDa The actual band is not consistent with the expectation.

UniProt: Q9NZQ7

Pathways: Cancer Immune Checkpoints