Recombinant CD276 antibody

Catalog No. ABIN7828078

This Rabbit Monoclonal antibody specifically detects CD276 in WB, FACS, IHC, IP and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for Recombinant CD276 antibody (ABIN7828078)

Target: CD276

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD276 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: A137

Product Details anti-CD276 Antibody

Purpose: Recombinant B7-H3/CD276 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human B7-H3/CD276 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000,IHC 1:200-1:1000,IF 1:50,FCM 1:50-1:100,IP 1:25-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD276

Target: CD276

Alternative Name: B7-H3/CD276

Background: B7H,UNQ,PRO,B7-H,B7RP,B7 homolog,B7H34Ig-B7-H,PSEC,4Ig-B7-H,CD276,4Ig-B7-H3,B7-H3,B7H3,B7RP-2,B7 homolog 3,B7H34Ig-B7-H3,CD276 antigen,CD276 Molecule,Costimulatory molecule,PSEC0249,UNQ309,PRO352,B7RP-2,4Ig-B7-H3,B7H3,B7-H3,CD276 antigen,May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 57 kDa

Observed MW: 110 kDa The actual band is not consistent with the expectation.

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints