Recombinant CD70 antibody

Catalog No. ABIN7828092

The Rabbit Monoclonal anti-CD70 antibody (Clone A550) (ABIN7828092) specifically detects CD70 in WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant CD70 antibody (ABIN7828092)

Target: CD70 (CD70 Molecule (CD70))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD70 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A550

Product Details anti-CD70 Antibody

Purpose: Recombinant CD70 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human CD70 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: CD70

Background: Tumor necrosis factor ligand superfamily member,TNFSF,CD70,CD27-L,CD27L,CD27LG,TNFSF7,TNLG8A,CD27 ligand,CD70 antigen,Tumor necrosis factor ligand superfamily member 7,Ki-24,CD27L,TNFSF7,CD 27L,CD 70,CD27 L,CD27 LG,CD70 Molecule,Ki 24 antigen,Ki24 antigen,member 7,sCD27 Ligand,soluble CD27 Ligand,Surface antigen CD70,TNFSF 7,Tumor necrosis factor (ligand) superfamily,CD70 is a type II transmembrane glycoprotein and a member of the tumor necrosis factor ligand superfamily (TNFSF), also known as CD27L and TNFSF7. It is normally expressed on medullary thymic epithelial cells. Its expression is induced on activated lymphoid cells (B cells, T cells, and NK cells) and dendritic cells. CD70 is a ligand for CD27, a co-stimulatory receptor that plays an important role in T cell activation and proliferation. CD70 overexpression has been reported in various tumors such as renal cell carcinoma, glioblastoma, and non-small cell lung carcinoma and it's being actively pursued as a therapeutic target. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 23 kDa

Observed MW: 27,54,81 kDa The actual band is not consistent with the expectation.

UniProt: P32970

Pathways: Cancer Immune Checkpoints