Recombinant CHD3 antibody

Catalog No. ABIN7828113

The Rabbit Monoclonal anti-CHD3 antibody (Clone A479) (ABIN7828113) specifically detects CHD3 in WB, IHC, IF and FACS. The antibody is reactive with Human and Rat samples.

Quick Overview for Recombinant CHD3 antibody (ABIN7828113)

Target: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CHD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: A479

Product Details anti-CHD3 Antibody

Purpose: Recombinant CHD3 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human CHD3 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50,FCM 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CHD3

Target: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Alternative Name: CHD3

Background: CHD,CHD3,Mi-2a,Mi2-ALPHA,ZFH,chromodomain helicase DNA binding protein 3,Chromodomain-helicase-DNA-binding protein 3(CHD3) is an enzyme that is encoded by the CHD3 gene in human. This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD3 is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Mutations in CHD3 gene cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 227 kDa

Observed MW: 260 kDa The actual band is not consistent with the expectation.

UniProt: Q12873