Recombinant CD39 antibody

Catalog No. ABIN7828168

This Rabbit Monoclonal antibody specifically detects CD39 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Recombinant CD39 antibody (ABIN7828168)

Target: CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD39 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A701

Product Details anti-CD39 Antibody

Purpose: Recombinant CD39 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD39

Target: CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

Alternative Name: CD39

Background: SPG,Ecto-ATP diphosphohydrolase,Ectonucleoside triphosphate diphosphohydrolase,ENTPD,ENTPD1,ATPDase,CD39,NTPDase-1,SPG64,CD 39,NTPDase1,Ecto-apyrase,Ectonucleoside triphosphate diphosphohydrolase 1,NTPDase 1,Ecto-ATP diphosphohydrolase 1,Lymphoid cell activation antigen,NTPDase-1,CD39 antigen,DKFZp686D194,DKFZp686I093,Ecto apyrase,Ecto ATP diphosphohydrolase,Ecto-ATPase 1,Ecto-ATPDase 1,ENTP1,ENTPD 1,FLJ40921,FLJ40959,CD39,also known as ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1), is a multi-pass membrane ectoenzyme that metabolizes adenosine-5'-triphosphate (ATP) to regulate purinergic signaling. Purinergic signaling by extracellular ATP and its metabolites regulate many biological processes, including vascular tone, digestion, neuronal function, and inflammation in both normal and diseased states. CD39 is expressed in endothelial cells in the vasculature to regulate local platelet purinergic signaling via metabolism of ATP to adenosine. Accordingly, CD39 regulates platelet activation aggregation and contributes to the antithrombotic properties of endothelial cells. ATP and its metabolites also finely modulate the activity of T cells and macrophages. Immunomodulation is regulated, in part, by the availability of extracellular ATP and adenosine, suggesting that CD39 may play an immunosuppressive role in the tumor microenvironment. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 58 kDa

Observed MW: 78 kDa The actual band is not consistent with the expectation.

UniProt: P49961