Recombinant EIF4G1 antibody

Catalog No. ABIN7828190

The Rabbit Monoclonal anti-EIF4G1 antibody is suitable to detect EIF4G1 in samples from Human and Mouse. It has been validated for WB and IHC.

Quick Overview for Recombinant EIF4G1 antibody (ABIN7828190)

Target: EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This EIF4G1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A669

Product Details anti-EIF4G1 Antibody

Purpose: Recombinant eIF4G1 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human eIF4G1 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000,IHC 1:500-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for EIF4G1

Target: EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))

Alternative Name: eIF4G1

Background: PARK,DKFZp686A,eIF 4 gamma,eIF-4-gamma,Eukaryotic translation initiation factor 4 gamma,IF4G,EIF4G1,EIF-4G1,EIF4F,EIF4G,EIF4GI,P220,PARK18,DKFZp686A1451,eIF 4 gamma 1,eIF 4G 1,eIF 4G1,EIF4 gamma,eIF-4G 1,eIF-4-gamma 1,Eukaryotic translation initiation factor 4 gamma 1,IF4G1,The initiation of translation is an important biological event and a variety of factors contribute to this process. Members of the eIF4 translation initiation factor family bind to the 5' m7GTP mRNA cap and unwind the mRNA secondary structure. The amino-terminal portion of eIF4G physically associates with eIF4E to stimulate the binding of eIF4E to the mRNA cap structure. eIF4G also interacts with eIF3 and eIF4A and serves as an adaptor molecule in the eIF4 complex. Moreover, eIF4G plays a role in internal ribosomal entry site (IRES)-mediated initiation of translation. The eIF4G family includes eIF4G1 (eIF4GI), eIF4G2 (p97, DAP5 or NAT1), and eIF4G3 (eIF4GII). These factors share a homologous sequence that provides for interaction with initiation factors eIF3 and eIF4A. Both eIF4G1 and eIF4G3 are involved in cap-dependent translation, while eIF4G2 plays a role in IRES-mediated translation of some genes during cell stress. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 175 kDa

Observed MW: 250 kDa The actual band is not consistent with the expectation.

UniProt: Q04637