Recombinant FGL1 antibody

Catalog No. ABIN7828204

This Rabbit Monoclonal antibody specifically detects FGL1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant FGL1 antibody (ABIN7828204)

Target: FGL1 (Fibrinogen-Like 1 (FGL1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FGL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A637

Product Details anti-FGL1 Antibody

Purpose: Recombinant FGL1 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human FGL1 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000,IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for FGL1

Target: FGL1 (Fibrinogen-Like 1 (FGL1))

Alternative Name: FGL1

Background: FGL,Fibrinogen-like protein,Liver fibrinogen-related protein,LFIRE,HP-041,Hepassocin,HPS,HFREP-1,LFIRE-1,HFREP1,Fibrinogen-like protein 1,Liver fibrinogen-related protein 1,FGL1,Fgl1,Hepassocin,HFREP1,HFREP-1,FGL 1,Fibrinogen like 1,Fibrinogen like protein 1,Fibrinogen related protein 1,Hepatocellular carcinoma related sequence,Hepatocyte derived fibrinogen related protein 1,Hepatocyte-derived fibrinogen-related protein 1,HFREP 1,HP 041,HP041,LFIRE 1,LFIRE1,Liver fibrinogen related protein 1,MFIRE 1,MGC108569,MGC12455,MGC37822,OTTHUMP00000122468,Fibrinogen-like protein 1 (FGL1), also known as hepassocin, is a secreted protein mainly expressed in liver and its expression is further enhanced following acute liver injury. FGL1 null mice have multiple metabolic abnormalities and are more prone to develop hepatocellular carcinoma under certain experimental conditions, suggesting FGL1 has diverse functions in vivo. More recently, FGL1 was found to be highly expressed in human cancer cells and function as an inhibitory ligand for LAG3. Blockade of the FGL1-LAG3 interaction stimulates tumor immunity in mouse models. In addition, a high plasma FGL1 level in human cancer patients is associated with a poor prognosis and resistance to anti-PD-1/PD-L1 immunotherapy. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 36 kDa

Observed MW: 34 kDa The actual band is not consistent with the expectation.

UniProt: Q08830